l(2)35Cf, DmS-II, BG:DS00929.12
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\TfIIS using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\TfIIS in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
α-amanitin has an inhibitory effect on TfIIS-mediated transcript cleavage, but has no effect on elongation or pycophosphorolysis.
TfIIS is necessary and sufficient to activate nascent transcript cleavage by RNA polymerase II during transcription of a dC-tailed template in vitro.
2 alleles are discussed but are not named.