FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)osp29
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General Information
Symbol
Df(2L)osp29
Species
D. melanogaster
Name
Deficiency (2L) outspread
FlyBase ID
FBab0001864
Feature type
chromosomal_deletion
Also Known As
Df(2L)osp29, osp29
Computed Breakpoints include

35B3;35E6

Features within 35B3--35E6
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(Ashburner et al., 1999.10.12, Grau et al., 1984)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, McNabb et al., 1996, Rodriguez et al., 1996, Roote et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Furukawa et al., 1992, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1983)
Breakpoints

35B3;35E6

(McNabb et al., 1996, Ashburner et al., 1983)

35B2-35B3;35E6

(Pauli et al., 1995, Schupbach and Wieschaus, 1989)

35B1-35B3;35E6

(Duffy et al., 1996, Rodriguez et al., 1996, Roote et al., 1996, Harbecke and Lengyel, 1995, Furukawa et al., 1992, Gubb et al., 1990)

35B1-35B2;35E6

(Grau et al., 1984)
Causes alleles
osp29
(Ashburner et al., 1999.10.12)
Carries alleles
Transposon Insertions
Formalized genetic data

Adh << bk1 << osp mol << BicC << bk2 << Ca-α1D

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Chia et al., 1985)

Left and/or right breakpoints mapped to the DNA (Chia, Karp, McGill and Ashburner, 1985, J. Mol. Biol. 186: 689-706)

Comments on Cytology

Ref: FBrf0038047.

(Grau et al., 1984)

Left limit of break 1 from polytene analysis (FBrf0039455) Right limit of break 1 from inclusion of osp (FBrf0087599) Limits of break 2 from polytene analysis (FBrf0039455)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Adh
(Roote, 1996.8)
Ankrd49
(Furukawa et al., 1992)
beat-Ia
(Ashraf et al., 1999)
BicC
(Eberl et al., 1998, Roote, 1996.8, Roote et al., 1996, Schupbach and Wieschaus, 1991, Tearle and Nusslein-Volhard, 1987, Mohler and Wieschaus, 1986, Grau et al., 1984)
CIAPIN1
(Furukawa et al., 1992, Ashburner et al., 1982)
ck
(Kiehart et al., 2004, Cai et al., 2001, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
Cul3
(Cai et al., 2001, Furukawa et al., 1992, Ashburner et al., 1982)
CycE
(Cai et al., 2001, BDGP Project Members, 1994-1999, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
DCTN5-p25
(Furukawa et al., 1992)
esg
(Cai et al., 2001, Rodriguez et al., 1996, Samakovlis et al., 1996, Kania et al., 1995, BDGP Project Members, 1994-1999, Furukawa et al., 1992)
Gli
(Cai et al., 2001, Auld et al., 1995)
l(2)35Cg
(Cai et al., 2001)
l(2)35Ch
(Cai et al., 2001)
l(2)35De
(Cai et al., 2001, Furukawa et al., 1992)
lace
(Cai et al., 2001, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
mol
(McNabb et al., 1996, Roote, 1996.8, Roote et al., 1996, Furukawa et al., 1992, Chia et al., 1985, Grau et al., 1984, Ashburner et al., 1982)
ms(2)35Eb
(Eberl et al., 1998)
Mtr4
(Cai et al., 2001, Furukawa et al., 1992)
ND-B17
(Cai et al., 2001)
osp
(Ashraf et al., 1999, McNabb et al., 1996, Roote, 1996.8, Roote et al., 1996)
PolD3
(Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
Rnmt
(Furukawa et al., 1992)
sna
(Das et al., 2016, Cai et al., 2001, Harbecke and Lengyel, 1995, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
stc
(Cai et al., 2001, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
Su(H)
(Furukawa et al., 1992, Grau et al., 1984)
TfIIS
(Cai et al., 2001, Furukawa et al., 1992)
Thg
(Furukawa et al., 1992, Chia et al., 1985)
Uxt
(Cai et al., 2001, Furukawa et al., 1992)
vas
(Cai et al., 2001, Furukawa et al., 1992, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1986)
vig
(Cai et al., 2001)
wek
(Cai et al., 2001)
wor
(Ashraf et al., 2004, Cai et al., 2001, Furukawa et al., 1992, Grau et al., 1984, Ashburner et al., 1982)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Viable but male sterile in combination with Df(2L)TE35B-9.

    (Ashburner et al., 1999)

    Does not suppress the zeste phenotype in a z1 w11E4; Tp(1;2)TE35B homologue.

    (Gubb et al., 1990)

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    The Df(2L)osp29 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Heterozygosity for Df(2L)osp29 results in 3.7% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    Mutant embryos have gastrulation defects.

    (Ashraf and Ip, 2001)

    Df(2L)osp29 embryos show defective neuroblast asymmetry.

    (Cai et al., 2001)

    Heterozygotes show a quantitative effect on wing shape in intervein regions C and D compared to wild type.

    (Palsson and Gibson, 2000)

    Df(2L)osp29 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces sterile male flies. These flies are female sterile.

    (Sawamura et al., 2000)

    Homozygous embryos show a gastrulation defect. The central and peripheral nervous systems are poorly differentiated.

    (Ashraf et al., 1999)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 10-24%.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Acts as a dosage sensitive maternal modifier of run : causes tergite defects in greater than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos are very abnormal compared to wild-type.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Chromosome has no effect on the physical interaction between tandemly duplicated copies of w+ and z1, despite having breakpoints within the critical region.

    (Gubb et al., 1990)

    Heterozygotes with Sco viable and without enhanced Sco phenotype

    Stocks (3)
    Notes on Origin
    Discoverer

    Detwiler.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Reported to not delete Adhr in error; see FBrf0141768 for correction.

    (Roote et al., 1996)

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    (Roote, 1996.8)
    Synonyms and Secondary IDs (8)
    References (68)