FB2026_03 , released September 17, 2026
Allele: Dsim\CoVIIaDel.W85.V86
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General Information
Symbol
Dsim\CoVIIaDel.W85.V86
Species
D. simulans
Name
FlyBase ID
FBal0277773
Feature type
allele
Associated gene
Dsim\CoVIIa
Associated Insertion(s)
Carried in Construct
Also Known As
cox7A (ΔTrp85, ΔVal86)
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Melvin et al., 2008)
Progenitor genotype
Cytology
Description

Deletion of two amino acids (Trp85 and Val86).

(Melvin et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Dsim\CoVIIaDel.W85.V86 mutants show higher fertility than heterozygous and wild-type controls.

      Homo- and heterozygous flies harbouring Dsim\CoVIIaDel.W85.V86 show reduced survival compared to wild-type.

      Older flies carrying homozygous Dsim\CoVIIaDel.W85.V86 display reduced physical activity compared to wild-type.

      (Ballard and Melvin, 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      COX7A (ΔTrp85, ΔVal86)
      (Melvin et al., 2008)
      Dsim\CoVIIaDel.W85.V86
      cox7A (ΔTrp85, ΔVal86)
      (Ballard and Melvin, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)