FB2026_02 , released June 18, 2026
Allele: Dmel\mir-308UAS.cDa
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General Information
Symbol
Dmel\mir-308UAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Daneshvar
FlyBase ID
FBal0277886
Feature type
allele
Associated gene
Dmel\mir-308
Associated Insertion(s)
Carried in Construct
P{UAS-mir-308.D}
Key Links
Transgenic product class
wild_type
(Daneshvar et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Daneshvar et al., 2013)
Mutagen
in vitro construct
(Daneshvar et al., 2013, Daneshvar and Goodliffe, 2012.10.11)
Progenitor genotype
Carried in construct
P{UAS-mir-308.D}
Cytology
Description

UASt regulatory sequences drive expression of a 300bp genomic fragment which contains mir-308.

(Daneshvar et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mir-308
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of mir-308Scer\UAS.cDa under the control of Scer\GAL4elav.Switch.PO, in combination with RU486 treatment to restrict expression to adulthood, does not lead to a significant difference in the recovery time from ethanol sedation, as compared to controls.

      (Ghezzi et al., 2016)

      Only 19 +/- 9% of animals expressing mir-308Scer\UAS.cDa under the control of Scer\GAL4da.G32 survive past 96 hours after egg deposition, compared to 77 +/- 6% of controls.

      (Daneshvar et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Suppressor of
      Statement
      Reference

      mir-308UAS.cDa, Scer\GAL4da.G32 is a suppressor | partially of lethal phenotype of MycUAS.cZa, Scer\GAL4da.G32

      (Daneshvar et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of both dmScer\UAS.cZa and mir-308Scer\UAS.cDa under the control of Scer\GAL4da.G32 results in an increased proportion of the animals surviving to 96 hours after egg deposition compared to expression of either construct alone.

      (Daneshvar et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mir-308Scer\UAS.cDa
      mir-308UAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Daneshvar
      Secondary FlyBase IDs
        References (4)