FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ten-aGE1914
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General Information
Symbol
Dmel\Ten-aGE1914
Species
D. melanogaster
Name
FlyBase ID
FBal0277974
Feature type
allele
Associated gene
Dmel\Ten-a
Associated Insertion(s)
P{EP}Ten-aGE1914
Carried in Construct
Also Known As
UAS-Ten-a
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}Ten-aGE1914
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of Ten-aGE1914 under the control of Scer\GAL4Mz19 partially disrupts the intermingling of olfactory receptor neuron (ORN) axons expressing Or88a and VA1d projection neuron (PN) dendrites which is normally seen in wild type. In addition, the position of the Scer\GAL4Mz19-expressing PN dendrites is shifted compared to wild type (although this alone is not enough to cause the disruption of the normal ORN axon-PN dendrite connections).

        Clonal expression (using MARCM) of Ten-aGE1914 under the control of Scer\GAL4Mz19 in VA1d/DC3 projection neurons, but not in DA1 PNs, causes mismatching of the PN dendrites with Or23a-expressing olfactory receptor neurons (ORNs) and (to a lesser extent) with Or67d-expressing ORNs.

        (Hong et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Ten-aGE1914
        Name Synonyms
        Secondary FlyBase IDs
          References (4)