FlyBase Allele Report: Dmel\mir-124[UAS.DsRed(Unk)]

General Information

Symbol

Dmel\mir-124^{UAS.DsRed(Unk)}

Species

D. melanogaster

Name

FlyBase ID

FBal0278008

Feature type

allele

Associated gene

Dmel\mir-124

Associated Insertion(s)

Carried in Construct

P{UAS-DsRed-mir-124.L}

Key Links

Transgenic product class

wild_type

(Bejarano et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Bejarano et al., 2012)

Mutagen

in vitro construct

(Bejarano et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-DsRed-mir-124.L}

Cytology

Description

UAS regulatory sequences drive expression of a DsRed(Unk) fluorescent protein. A genomic fragment containing the mir-124 pre-miRNA hairpin has been inserted into the DsRed(Unk) 3'UTR.

(Bejarano et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

mir-124

Tagged with

DsRed(Unk)

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4²²¹

(Sun et al., 2012)

lethal - all die before end of pupal stage, with Scer\GAL4^sd-SG29.1

(Bejarano et al., 2012)

some die during pupal stage, with Scer\GAL4^sd-SG29.1

(Bejarano et al., 2012)

visible, with Scer\GAL4^Bx-MS1096

(Bejarano et al., 2012)

Phenotype Manifest In

dendrite | larval stage, with Scer\GAL4²²¹

(Sun et al., 2012)

larval dorsal multidendritic neuron ddaD | larval stage, with Scer\GAL4²²¹

(Sun et al., 2012)

larval dorsal multidendritic neuron ddaE | larval stage, with Scer\GAL4²²¹

(Sun et al., 2012)

wing, with Scer\GAL4^Bx-MS1096

(Bejarano et al., 2012)

Detailed Description

Statement

Reference

Expression of mir-124^{Scer\UAS.T:Disc\RFP} under the control of Scer\GAL4²²¹ results in a decrease in the average number of dendritic branches in the ddaD and ddaE neurons of larvae.

(Sun et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

mir-124^{Scer\UAS.T:Disc\RFP}

mir-124^{UAS.DsRed(Unk)}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close