FB2026_02 , released June 18, 2026
Allele: Dmel\tslRNAi.UAS
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General Information
Symbol
Dmel\tslRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0279804
Feature type
allele
Associated gene
Dmel\tsl
Associated Insertion(s)
Carried in Construct
P{UAS-tsl.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Furriols et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Furriols et al., 2007)
Mutagen
in vitro construct
(Furriols et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-tsl.RNAi}
Cytology
Description

UAS regulatory sequences drive expression of a 510bp inverted repeat of tsl sequences which are separated by an H intron.

(Furriols et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
tsl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Pupariation is delayed compared to controls when tsldsRNA.Scer\UAS is expressed under the control of Scer\GAL4phm.PO.

      (Grillo et al., 2012)

      Embryos expressing tsldsRNA.Scer\UAS under the control of Scer\GAL4slbo.2.6 have anterior terminal structure defects. The dorsal bridge is absent in 100% embryos.

      No anterior terminal structure defects are seen in embryos expressing tsldsRNA.Scer\UAS under the control of Scer\GAL455B.

      No anterior terminal structure defects are seen in embryos expressing tsldsRNA.Scer\UAS under the control of Scer\GAL4c306.

      Embryos expressing tsldsRNA.Scer\UAS under the control of Scer\GAL455B and Scer\GAL4c306 exhibit anterior terminal structure defects. The dorsal bridge is absent in 61% of embryos.

      (Furriols et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tslRNAi.UAS
      tsldsRNA.Scer\UAS
      tsldsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (5)