Imprecise excision of the progenitor insertion, resulting in a 1191bp deletion spanning the region from nucleotides -65 to +1126 relative to the predicted Sdr transcription start site.
Homozygous eggs and newly hatched first instar larvae are identical in size to controls. However, a small increase in body weight compared to controls is detectable at the early second instar, and this becomes more pronounced in third instar larvae, such that body weight is increased 20% compared to controls in homozygous late third instar larvae.
Homozygous and Sdr1/SdrDf adult males and females show an increase in body weight compared to controls.
Adult wing area is increased in homozygous adults. This is due to an increase in both cell size and cell number compared to controls.
Mutants show an increase in body size compared to wild-type controls, regardless of nutrient conditions. Mutant animals grown on only 10% the normal amount of food undergo puparium formation to a similar degree as controls, but the mutant pupae show a significantly lower rate of eclosion than controls under these conditions.
