Recombination between the two progenitor insertions has resulted in the deletion of the genomic sequence between them, which removes the entire Sdr transcription unit.
Deletion resulting from recombination between two progenitor insertions.
Homozygous eggs and newly hatched first instar larvae are identical in size to controls. However, a small increase in body weight compared to controls is detectable at the early second instar, and this becomes more pronounced in third instar larvae, such that body weight is increased 20% compared to controls in homozygous late third instar larvae.
Homozygous and Sdr1/SdrDf adult males and females show an increase in body weight compared to controls.
Adult wing area is increased in homozygous adults. This is due to an increase in both cell size and cell number compared to controls.
Mutants show an increase in body size compared to wild-type controls, regardless of nutrient conditions. Mutant animals grown on only 10% the normal amount of food undergo puparium formation to a similar degree as controls, but the mutant pupae show a significantly lower rate of eclosion than controls under these conditions.
