FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SnapinUAS.cDa
Open Close
General Information
Symbol
Dmel\SnapinUAS.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0282368
Feature type
allele
Associated gene
Dmel\Snapin
Associated Insertion(s)
Carried in Construct
P{UAS-Snapin.D}
Key Links
Transgenic product class
cDNA
(Dickman et al., 2012)
wild_type
(Dickman et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Dickman et al., 2012)
wild_type
(Dickman et al., 2012)
Mutagen
in vitro construct
(Dickman et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Snapin.D}
Cytology
Description

UASt regulatory sequences drive expression of Snapin cDNA sequences.

(Dickman et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Snapin
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of snapinScer\UAS.cDa in the nervous system under the control of Scer\GAL4elav-C155 does not potentiate synaptic transmission.

      (Dickman et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of SnapinScer\UAS.cDa in motorneurons (under the control of Scer\GAL4VGlut-OK371) in Dysbe01028; Df(2L)Exel6277 double heterozygotes restores homeostasis towards control levels (although this rescue is not complete).

      The presynaptic homeostatic plasticity that normally occurs after application of the postsynaptic glutamate receptor antagonist PhTx is blocked in Snap25124/+ ; Df(2L)Exel6277/+ double heterozygous larvae. Synaptic homeostasis can be restored in the double heterozygotes through expression of SnapinScer\UAS.cDa in the motorneurons (under the control of Scer\GAL4elav-C155).

      (Dickman et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SnapinScer\UAS.cDa
      SnapinUAS.cDa
      snapinScer\UAS.cDa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)