FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cyp6d2NT
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General Information
Symbol
Dmel\Cyp6d2NT
Species
D. melanogaster
Name
FlyBase ID
FBal0282693
Feature type
allele
Associated gene
Dmel\Cyp6d2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Thomas et al., 2013)
Progenitor genotype
Cytology
Description

Amino acid replacement: N438D.

(Thomas et al., 2013)

Little of no transcript is produced in this mutation.

(Thomas et al., 2013)

Amino acid replacement: N439T.

(Thomas et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:22,652,974..22,652,974 [-]
Nucleotide change:

A22652974C

Amino acid change:

N439T | Cyp6d2-PA

Reported amino acid change:

N439T

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Thomas et al., 2013)
point_mutation
2R:22,652,978..22,652,978 [-]
Nucleotide change:

A22652978G

Amino acid change:

N438D | Cyp6d2-PA

Reported amino acid change:

N438D

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Thomas et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies are sensitive to camptothecin.

      (Thomas et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Cyp6d2NT is rescued by Cyp6d2+tTa

      (Thomas et al., 2013)
      Comments

      Cyp6d2+tTa rescues the camptothecin sensitivity of Cyp6d2NT flies.

      (Thomas et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Cyp6d2NT
      (Thomas et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)