Immediately after exposure to acoustic trauma, control and nrv3¹⁵/+ flies have similar reductions in sound-evoked potentials (SEPs). One day post-trauma, mutant flies show a weaker recovery in SEPs than controls. Seven days post-trauma, the mutant flies still have significantly reduced SEPs, whereas controls flies have recovered.

The mitochondria within JO neurons of nrv3¹⁵/+ flies not exposed to acoustic trauma generally have a smaller cross-sectional area than controls. After trauma, the reduction in mitochondrial area seen in controls is more immediate and more pronounced in mutants.