FB2026_03 , released September 17, 2026
Allele: Dmel\Lsm11F27A.N28A.Tag:V5
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General Information
Symbol
Dmel\Lsm11F27A.N28A.Tag:V5
Species
D. melanogaster
Name
FlyBase ID
FBal0284309
Feature type
allele
Associated gene
Dmel\Lsm11
Associated Insertion(s)
Carried in Construct
PBac{V5-Lsm11.F27A.N28A}
Key Links
Transgenic product class
missense_variant
(Burch et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Burch et al., 2011)
Mutagen
in vitro construct
(Burch et al., 2011)
Progenitor genotype
Carried in construct
PBac{V5-Lsm11.F27A.N28A}
Cytology
Description

An endogenous Lsm11 promoter drives expression of mutated Lsm11 coding sequences (amino acid replacements F27A and N28A), tagged at the N-terminal with Tag:V5 and is inserted into 22A3 on the 2nd chromosome.

(Burch et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Lsm11
Encoded product / tool
Lsm11
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Lsm11F27A.N28A.T:SV5\V5 in a Lsm11c02047 mutant background fails to restore His3 mRNA processing.

      (Burch et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Lsm11F27A.N28A.Tag:V5 fails to rescue Lsm11c02047

      (Burch et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lsm11F27A.N28A.T:SV5\V5
      Lsm11F27A.N28A.Tag:V5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)