FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syngr2
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General Information
Symbol
Dmel\Syngr2
Species
D. melanogaster
Name
FlyBase ID
FBal0284663
Feature type
allele
Associated gene
Dmel\Syngr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Stevens et al., 2012)
Mutagen
P-element activity
(Stevens et al., 2012)
Progenitor genotype
P{lacW}l(2)SH0644SH0644
(Stevens et al., 2012)
Cytology
Description

Excision of the P{lacW} element in P{lacW}l(2)SH0644SH0644 has resulted in a 1.7 kb deletion that removes the first exon of Syngr.

(Stevens et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Syngr2 mutant animals are viable, fertile and appear behaviourally normal. They develop at a similar rate and have a normal lifespan compared to control animals. Syngr2 mutant males are capable of performing all aspects of the courtship ritual.

      At Syngr2 mutant third instar larval neuromuscular junctions, overall synaptic morphology is normal with no obvious overgrowth, undergrowth or satellite boutons. The total number of synaptic boutons at muscle 6/7 of segment A3 is unchanged compared with controls. There is also no significant difference in muscle size.

      (Stevens et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Syngr2
      gyr2
      (Stevens et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)