FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\HsfUAS.GFP
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General Information
Symbol
Dmel\HsfUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0285336
Feature type
allele
Associated gene
Dmel\Hsf
Associated Insertion(s)
Carried in Construct
P{UAS-Hsf.GFP}
Key Links
Transgenic product class
wild_type
(Salamanca et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Salamanca et al., 2011)
Mutagen
in vitro construct
(Salamanca et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-Hsf.GFP}
Cytology
Description

UAS regulatory sequences drive expression of Hsf coding sequences tagged with GFP.

(Salamanca et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsf
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of HsfScer\UAS.T:Avic\GFP in the salivary glands under the control of Scer\GAL4c739 results in abnormally small salivary glands.

      (Salamanca et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Ubiquitous expression of HsfScer\UAS.T:Avic\GFP under the control of Scer\GAL4αTub84B.PL suppresses the lethality found in Zzzz\aptamerHsf.X8.Scer\UAS expressing animals. The wing notching defect found in these flies is not affected by HsfScer\UAS.T:Avic\GFP expression.

      Co-expression of Zzzz\aptamerHsf.X8.Scer\UAS with HsfScer\UAS.T:Avic\GFP in the salivary glands (under the control of Scer\GAL4c739) restores salivary gland morphology to nearly wild-type size.

      The high frequencies of lethality seen in flies with high-level systemic HsfScer\UAS.T:Avic\GFP expression (under the control of Scer\GAL4αTub84B.PL) is effectively suppressed by Zzzz\aptamerHsf.X8.Scer\UAS co-expression, resulting in viable and fertile animals.

      (Salamanca et al., 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HsfScer\UAS.T:Avic\GFP
      HsfUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)