FlyBase Allele Report: Dmel\jumu[X3]

General Information

Symbol

Dmel\jumu^X3

Species

D. melanogaster

Name

FlyBase ID

FBal0286393

Feature type

allele

Associated gene

Dmel\jumu

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Sugimura et al., 2000)

Progenitor genotype

Cytology

Description

X-ray irradiation generates a >4kb deletion in jumu that removes the first exon.

(Sugimura et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Sugimura et al., 2000)

Phenotype Manifest In

embryo

(Sugimura et al., 2000)

embryonic head

(Sugimura et al., 2000)

larval neuron

(Sugimura et al., 2000)

wing disc | somatic clone

(Sugimura et al., 2000)

Detailed Description

Statement

Reference

jumu^X3 embryos are defective in head involution, displaying an anterior open phenotype. Some jumu^X3 mutants show a defect in dorsal closure and in germ band retraction. In jumu^X3 embryos, the dorsal epidermal cells only partially elongate. These embryos exhibit loss of a large number of both CNS and PNS neurons. Occasionally, all or most of the CNS neurons in a hemisegment are lost.

(Sugimura et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dwhn^X3

(Sugimura et al., 2000)

jumu^X3

(Li et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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