FB2026_02 , released June 18, 2026
Allele: Mmus\Ucp1UAS.cFa
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General Information
Symbol
Mmus\Ucp1UAS.cFa
Species
M. musculus
Name
Saccharomyces cerevisiae UAS construct a of Fridell
FlyBase ID
FBal0287936
Feature type
allele
Associated gene
Mmus\Ucp1
Associated Insertion(s)
Carried in Construct
P{UAS-mucp1.F}
Transgenic product class
cDNA
(Fridell et al., 2009)
wild_type
(Fridell et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Fridell et al., 2009)
wild_type
(Fridell et al., 2009)
Mutagen
in vitro construct
(Fridell et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-mucp1.F}
Cytology
Description

UAS regulates expression of a full-length Mmus\Ucp1 cDNA.

(Fridell et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mmus\Ucp1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Insulin-like peptide-producing cells in Scer\GAL4Ilp2.PR Mmus\Ucp1Scer\UAS.cFa flies are morphologically indistinguishable from those of controls.

      Under normal growth conditions, insulin-like peptide-producing cells in Scer\GAL4Ilp2.PR Mmus\Ucp1Scer\UAS.cFa adult brains show a 21-51% decrease in steady-state Ca[2+] levels.

      Under fasting conditions, the hemolymph of Scer\GAL4Ilp2.PR Mmus\Ucp1Scer\UAS.cFa flies has up to a 29% increase in circulating sugars (glucose + trehalose) compared to controls.

      Scer\GAL4Ilp2.PR-mediated expression of Mmus\Ucp1Scer\UAS.cFa extends adult lifespan and renders flies more resistant to oxidative and starvation stress compared to controls. Average egg laying activities and spontaneous physical activity are comparable to controls.

      Scer\GAL4Ilp2.PR Mmus\Ucp1Scer\UAS.cFa flies have an average of 26% increase in glycogen content but no noticeable increase in lipid content.

      (Fridell et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmus\Ucp1Scer\UAS.cFa
      Mmus\Ucp1UAS.cFa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Fridell
      Secondary FlyBase IDs
        References (1)