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General Information
Symbol
Dmel\Dsor1dsRNA.UAS.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0290180
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an RNAi construct targeting Dsor1.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Dsor1dsRNA.Scer\UAS.cUa RNAi under the control of Scer\GAL4esg-NP5130 (using tub-Gal80[ts] to limit the time of RNAi expression) results in a suppression of regeneration-associated proliferation of intestinal stem cells in the adult midgut upon Pseudomonas entomophila enteric infection.

Hearts from Scer\GAL4tin.CΔ4>Dsor1dsRNA.Scer\UAS.cUa flies show slightly increased end-diastolic dimensions, significantly increased end-systolic dimensions, and thinner heart walls compared with controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The inhibition of the regeneration-associated proliferation of intestinal stem cells in adult midgut upon infection with Pseudomonas entomophila characteristic for flies expressing Dsor1dsRNA.Scer\UAS.cUa RNAi under the control of Scer\GAL4esg-NP5130 (using tub-Gal80[ts] to limit the time of RNAi expression) can be reverted by co-expression of Ets21CScer\UAS.cUa.

Xenogenetic Interactions
Statement
Reference

Cardiac-specific co-expression of Hsap\RAF1gof.Scer\UAS does not change heart wall thickness and cardiomyocyte architecture in Scer\GAL4tin.CΔ4>Dsor1dsRNA.Scer\UAS.cUa expressing flies.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Dsor1dsRNA.Scer\UAS.cUa
Dsor1dsRNA.UAS.cUa
Name Synonyms
Secondary FlyBase IDs
    References (2)