FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SERCAkum170.tinC
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General Information
Symbol
Dmel\SERCAkum170.tinC
Species
D. melanogaster
Name
FlyBase ID
FBal0290412
Feature type
allele
Associated gene
Dmel\SERCA
Associated Insertion(s)
Carried in Construct
P{tinC-Ca-P60.kum170}
Key Links
Transgenic product class
missense_variant
(Abraham and Wolf, 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Abraham and Wolf, 2013)
Mutagen
in vitro construct
(Abraham and Wolf, 2013)
Progenitor genotype
SERCAKum170
(Abraham and Wolf, 2013)
Carried in construct
P{tinC-Ca-P60.kum170}
Cytology
Description

The tinC enhancer drives expression of the mutant Ca-P60A coding sequence from Ca-P60AKum170.

(Abraham and Wolf, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
tin
Encoded product / tool
SERCA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      As in wild type, no paralysis is seen when Ca-P60Akum170.tinC is expressed in flies exposed to heat shock. However cardiac dilation and diminished cardiac function are seen. Heart rate is not reduced.

      (Abraham and Wolf, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ca-P60Akum170.tinC
      SERCAkum170.tinC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)