FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Zmynd10V16G.Venus
Open Close
General Information
Symbol
Dmel\Zmynd10V16G.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0290980
Feature type
allele
Associated gene
Dmel\Zmynd10
Associated Insertion(s)
Carried in Construct
P{Zmynd10-mVenus.V16G}
Key Links
Genomic Maps

Transgenic product class
missense_variant
(Moore et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Moore et al., 2013)
Mutagen
in vitro construct
(Moore et al., 2013)
Progenitor genotype
Carried in construct
P{Zmynd10-mVenus.V16G}
Cytology
Description

Amino acid replacement: V16G.

(Moore et al., 2013)

A mutated form of the Zmynd10 genomic region, including 1.5kb of upstream flanking sequence is fused at the C-terminal with Venus.

(Moore et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
Zmynd10
Encoded product / tool
Zmynd10
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:13,026,319..13,026,319 [-]
Nucleotide change:

T13026319G

Amino acid change:

V14G | Zmynd10-PA

Reported amino acid change:

V14G

Comment:

Analogous mutation in human ZMYND10 implicated in ciliary dyskinesia, primary, 22; mutation carried on in vitro construct; site of nucleotide substitution in fly gene and specific disease association inferred by FlyBase curator.

(Moore et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      This allele represents a human variant implicated in disease.
      (Moore et al., 2013)
      ZMYND10:p.Val16Gly
      (FlyBase curators, 2019-)
      Variants Synonym(s)
      Associated human disease model(s)
      External database links
      ClinVar: ZMYND10_66021
      Comments concerning this variant
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Zmynd10V16G.Venus partially rescues Zmynd10EY10866

      (Moore et al., 2013)
      Comments

      Fertility is partially restored in Zmynd10EY10866 mutants in a Zmynd10T:Avic\GFP-YFP.Venus background.

      (Moore et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Zmynd10V16G.T:Avic\GFP-YFP.Venus
      Zmynd10V16G.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (2)