FB2026_02 , released June 18, 2026
Allele: Dmel\Fmr1A158T.EP3517
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General Information
Symbol
Dmel\Fmr1A158T.EP3517
Species
D. melanogaster
Name
FlyBase ID
FBal0291192
Feature type
allele
Associated gene
Dmel\Fmr1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Reeve et al., 2008)
Progenitor genotype
P{EP}EP3517
(Reeve et al., 2008)
Cytology
Description

Fmr1A158T.EP3517 carries both the P{EP} insertion present in the progenitor allele and the amino acid replacement in the Fmr1 coding region.

(Reeve et al., 2008)

Amino acid replacement: A158T.

(Reeve et al., 2008)

Nucleotide substitution: G?A

(Reeve et al., 2008)

Base change GCC->ACC.

(Reeve et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:10,105,678..10,105,678 [-]
Nucleotide change:

G10105678A

Reported nucleotide change:

G?A

Amino acid change:

A158T | Fmr1-PA; A158T | Fmr1-PB; A158T | Fmr1-PC; A158T | Fmr1-PD; A120T | Fmr1-PE; A120T | Fmr1-PF; A206T | Fmr1-PG; A206T | Fmr1-PH; A120T | Fmr1-PI; A158T | Fmr1-PJ; A158T | Fmr1-PK

Reported amino acid change:

A158T

(Reeve et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      A mutation that suppresses the lethality caused when a Scer\GAL4 driver is used to overexpress Fmr1 from the P{EP}Fmr1EP3517 insertion.

      (Reeve et al., 2008)

      Separable from: P{EP}Fmr1EP3517.

      (Reeve et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Fmr1A158T.EP3517
      W5
      (Reeve et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)