FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Odc1UAS.cGa
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General Information
Symbol
Dmel\Odc1UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS promoter construct a of Gupta
FlyBase ID
FBal0291455
Feature type
allele
Associated gene
Dmel\Odc1
Associated Insertion(s)
Carried in Construct
P{UAS-Odc1.G}
Key Links
Transgenic product class
cDNA
(Gupta et al., 2013)
wild_type
(Gupta et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Gupta et al., 2013)
wild_type
(Gupta et al., 2013)
Mutagen
in vitro construct
(Gupta et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Odc1.G}
Cytology
Description

UASt regulatory sequences drive expression of a Odc1 cDNA (clone GH13851).

(Gupta et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Odc1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  myotonic dystrophy type 2
      modeled by CNBPGD7370
      (Coni et al., 2021)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Scer\GAL4Appl.G1a>Odc1Scer\UAS.cGa are effectively protected from age-induced memory impairment (AMI) that characterises wild-type flies in both olfactory short-term and intermediate-term memory performance assays. Scer\GAL4Appl.G1a>Odc1Scer\UAS.cGa flies show almost identical test scores to aged flies in which AMI is suppressed by spermidine-feeding.

      Expression of Odc1Scer\UAS.cGa in mushroom body Kenyon cells using Scer\GAL4ey-OK107 has no effect on intermediate-term (ITM) and olfactory short-term memory (STM) scores compared to aged-matched controls (3 days of age). At 30 days of age, however, Scer\GAL4ey-OK107>Odc1Scer\UAS.cGa flies exhibit considerably higher STM and ITM scores when compared with aged-matched genetic controls.

      (Gupta et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Odc1Scer\UAS.cGa
      Odc1UAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS promoter construct a of Gupta
      Secondary FlyBase IDs
        References (3)