FlyBase Allele Report: Dmel\ttm50[GLC01620]

General Information

Symbol

Dmel\ttm50^GLC01620

Species

D. melanogaster

Name

FlyBase ID

FBal0291909

Feature type

allele

Associated gene

Dmel\ttm50

Associated Insertion(s)

Carried in Construct

P{TRiP.GLC01620}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.GLC01620}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GLC01620

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | pupal stage, with Scer\GAL4^ppk.PG

(Metwally et al., 2021)

increased size | pupal stage, with Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Phenotype Manifest In

dendrite | pupal stage, with Scer\GAL4^ppk.PG

(Metwally et al., 2021)

larval multidendritic class IV neuron | pupal stage, with Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Detailed Description

Statement

Reference

The expression of ttm50^GLC01620 under the control of Scer\GAL4^ppk.PG results in dendrite pruning defects in class IV da neurons at 14h APF.

(Metwally et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Scer\GAL4^ppk.PG, ttm50^GLC01620 has abnormal neuroanatomy | pupal stage phenotype, non-suppressible by CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Scer\GAL4^ppk.PG, ttm50^GLC01620 has increased size | pupal stage phenotype, non-suppressible by CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Suppressor of

Statement

Reference

ttm50^GLC01620, Scer\GAL4^ppk.PG is a suppressor of abnormal neuroanatomy | pupal stage phenotype of CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

ttm50^GLC01620, Scer\GAL4^ppk.PG is a suppressor of decreased size | pupal stage phenotype of CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Scer\GAL4^ppk.PG, ttm50^GLC01620 has larval multidendritic class IV neuron | pupal stage phenotype, non-suppressible by CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Scer\GAL4^ppk.PG, ttm50^GLC01620 has dendrite | pupal stage phenotype, non-suppressible by CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Suppressor of

Statement

Reference

ttm50^GLC01620, Scer\GAL4^ppk.PG is a suppressor of larval multidendritic class IV neuron | pupal stage phenotype of CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

ttm50^GLC01620, Scer\GAL4^ppk.PG is a suppressor of dendrite | pupal stage phenotype of CalpA^UAS.cMa, Scer\GAL4^ppk.PG

(Metwally et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

44642

y¹ v¹; P{TRiP.GLC01620}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ttm50^GLC01620

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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