FlyBase Allele Report: Dmel\Ahcy[HMC03222]

General Information

Symbol

Dmel\Ahcy^HMC03222

Species

D. melanogaster

Name

FlyBase ID

FBal0292397

Feature type

allele

Associated gene

Dmel\Ahcy

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC03222}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC03222}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC03222

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | light conditional, with Scer\GAL4^GMR.long

(Stanhope et al., 2025)

abnormal stress response | light conditional, with Scer\GAL4^GMR.long

(Stanhope et al., 2025)

short lived | RU486 conditional, with Scer\GAL4^{Act5C.Switch.PR}

(Parkhitko et al., 2016)

short lived | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Parkhitko et al., 2016)

Phenotype Manifest In

rhabdomere | light conditional, with Scer\GAL4^GMR.long

(Stanhope et al., 2025)

Detailed Description

Statement

Reference

Expression of Ahcy^HMC03222 driven by Scer\GAL4^{Act5C.Switch.PR} or Scer\GAL4^{elav.Switch.PO} (in males fed RU486 during adulthood) significantly shortens lifespan compared to controls.

(Parkhitko et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

51477

y¹ v¹; P{TRiP.HMC03222}attP40/CyO

NIG-Fly

HMC03222

y¹ v¹; P{TRiP.HMC03222}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ahcy13^HMC03222

Ahcy^HMC03222

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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