FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Gpx1UAS.cMa
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General Information
Symbol
Mmus\Gpx1UAS.cMa
Species
M. musculus
Name
Saccharomyces cerevisiae UAS construct a of Mason
FlyBase ID
FBal0294774
Feature type
allele
Associated gene
Mmus\Gpx1
Associated Insertion(s)
Carried in Construct
P{UAS-mGpx1.M}
Transgenic product class
wild_type
(Mason et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Mason et al., 2013)
Mutagen
in vitro construct
(Mason et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-mGpx1.M}
Cytology
Description

UASt regulatory sequences drive expression of Mmus\Gpx1.

(Mason et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\Gpx1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Huntington's disease
      modeled by Hsap\HTTQ93.ex1.UAS
      (Mason et al., 2013)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of Mmus\Gpx1Scer\UAS.cMa partially suppresses the progressive photoreceptor rhabdomere degeneration seen in flies expressing Hsap\HTTQ93.ex1p.Scer\UAS under the control of Scer\GAL4elav-C155.

      Co-expression of Mmus\Gpx1Scer\UAS.cMa suppresses the reduced locomotor activity seen in flies expressing Hsap\HTTQ93.ex1p.Scer\UAS under the control of Scer\GAL4elav-C155.

      Co-expression of Mmus\Gpx1Scer\UAS.cMa completely suppresses the loss of the small lateral ventral neurons seen in flies expressing Hsap\HTTQ93.ex1p.Scer\UAS under the control of Scer\GAL4P2.4.Pdf.

      (Mason et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmus\Gpx1Scer\UAS.cMa
      Mmus\Gpx1UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Mason
      Secondary FlyBase IDs
        References (1)