FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\RAB7AUAS.N.GFP
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General Information
Symbol
Hsap\RAB7AUAS.N.GFP
Species
H. sapiens
Name
FlyBase ID
FBal0295669
Feature type
allele
Associated gene
Hsap\RAB7A
Associated Insertion(s)
Carried in Construct
P{UAS-GFP-RAB7A}
Key Links
Transgenic product class
wild_type
(Janssens et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Janssens et al., 2014)
Mutagen
in vitro construct
(Janssens et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-GFP-RAB7A}
Cytology
Description

UAS regulatory sequences drive expression of wild-type full-length Hsap\RAB7A coding sequences tagged at the N-terminal with GFP.

(Janssens et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\RAB7A
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larvae expressing Hsap\RAB7AScer\UAS.N.T:Avic\GFP under the control of Scer\GAL4D42 does not exhibit any defects in locomotion.

      Flies expressing Hsap\RAB7AScer\UAS.N.T:Avic\GFP in sensory neurons under the control of Scer\GAL412.1 display normal themosensory activity, with less than 10% of flies remaining on a hot area (30[o]C) of a plate and not moving to a prefered colder area (at 22[o]C).

      Larvae expressing Hsap\RAB7AScer\UAS.N.T:Avic\GFP under the control of Scer\GAL412.1 do not exhibit any motor defects.

      Expression of Hsap\RAB7AScer\UAS.N.T:Avic\GFP under the control of Scer\GAL4221 (which drives expression in three sensory neurons per hemisegment) reveals that expression does not affect neuronal morphology or the size and complexity of the dendritic tree.

      (Janssens et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\RAB7AScer\UAS.N.T:Avic\GFP
      Hsap\RAB7AUAS.N.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)