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General Information
Symbol
Dmel\Vps16Ad116
Species
D. melanogaster
Name
FlyBase ID
FBal0296358
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Comment:

Inferred boundaries of a 926 bp deletion resulting from the imprecise excision of P{GSV2}GS5053, which extends from the insertion site into the Vps16A gene.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the P{GSV2} element in P{GSV2}GS5053 has resulted in a 926bp deletion starting from the P-element insertion site, deleting the protein-coding sequences in exons 1-3 and parts of exon 4 of Vps16A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Autolysosome formation is inhibited in the fat body cells of starved Vps16Ad116/Df(3R)ED5339 mutant wandering third instar larvae. Large number of autophagosomes are observed. Numerous dense organelles are seen, which are usually round and smaller than the autolysosomes observed in controls. A subset of these vesicles contain recognisable remnants of cytoplasmic material, such as mitochondrion.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)