FB2026_02 , released June 18, 2026
Allele: Dmel\Als2UAS.Tag:HA
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General Information
Symbol
Dmel\Als2UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0296466
Feature type
allele
Associated gene
Dmel\Als2
Associated Insertion(s)
Carried in Construct
P{UAS-Als2.WT}
Key Links
Transgenic product class
wild_type
(Takayama et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Takayama et al., 2014)
Mutagen
in vitro construct
(Takayama et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Als2.WT}
Cytology
Description

UAS regulatory sequences drive expression of the full-length coding sequence of Als2, that is tagged with Tag:HA.

(Takayama et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Als2
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Als2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Ubi has no effect on climbing ability in 1 and 2 week old adults compared to age-matched controls.

      Expression of Als2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4VGlut-OK371 results in a significant reduction in climbing ability in 1 and 2 week old adults compared to age-matched controls.

      (Takayama et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Ubi.PU/Als2UAS.Tag:HA rescues Als2Ex44

      (Takayama et al., 2014)
      Comments

      Expression of Als2Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Ubi rescues the reduced climbing ability of 2 week old Als2Ex44 homozygotes.

      (Takayama et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Als2Scer\UAS.T:Ivir\HA1
      Als2UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)