FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ATP8B2
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General Information
Symbol
Dmel\ATP8B2
Species
D. melanogaster
Name
FlyBase ID
FBal0297374
Feature type
allele
Associated gene
Dmel\ATP8B
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ha et al., 2014)
Progenitor genotype
Cytology
Description

The allele carries a 56-bp deletion in exon 17 of ATP8B that is predicted to produce a frameshift mutation and a truncated product.

(Ha et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The mutant is unresponsive to 1% cVA (11-cis-vaccenyl acetate) and also lacks normal spontaneous action potentials in the absence of cVA. Approximately half of the Or67d-neurons from this line are insensitive to all concentrations of cVA.

      (Ha et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ATP8B2
      Z3-3278
      (Ha et al., 2014)
      dATP8B2
      (Ha et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)