FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mora2
Open Close
General Information
Symbol
Dmel\mora2
Species
D. melanogaster
Name
FlyBase ID
FBal0298313
Feature type
allele
Associated gene
Dmel\mora
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    A 1 bp deletion at codon 134 (between the two CHORD domains) that causes a frame-shift that results in a premature STOP codon at M172 in the 2nd CHORD domain.

    (Shimono et al., 2014)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    deletion
    3R:24,186,941..24,186,941 [+]
    Comment:

    A one base pair deletion GCCATT(G)AGGTG in codon E135 leads to a frameshift and early translation termination.

    (Shimono et al., 2014)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Homozygous neurons (generated via a Scer\FLP1SOP / MARCM method) generate miniature (i.e. a proportionally scaled down microcopy of wild type) dendritic arbors regardless of body size/nutritional input: dendritic segment length is reduced without simplifying the branching pattern in both fed and starved flies.

        (Shimono et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        mora2 is rescued by mora+t4.8

        (Shimono et al., 2014)
        Comments

        P{CHORD4.8} almost fully rescues the miniature dendritic arbor phenotype seen in CHORD2 neurons.

        (Shimono et al., 2014)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Isolated as a shared background mutation on the PBac{SAstopDsRed}LL04611 and PBac{SAstopDsRed}LL04133 chromosomes.

        (Shimono et al., 2014)

        Separable from: PBac{SAstopDsRed}LL04611.

        (Shimono et al., 2014)

        Separable from: PBac{SAstopDsRed}LL04133.

        (Shimono et al., 2014)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        CHORD2
        (Shimono et al., 2014)
        mora2
        Name Synonyms
        Secondary FlyBase IDs
          References (1)