FlyBase Allele Report: Dmel\Nsun1[HMC04440]

General Information

Symbol

Dmel\Nsun1^HMC04440

Species

D. melanogaster

Name

FlyBase ID

FBal0299448

Feature type

allele

Associated gene

Dmel\Nsun1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC04440}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC04440}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC04440

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^da.G32

(Parra-Torres et al., 2026)

lethal, with Scer\GAL4^elav.PLu

(Parra-Torres et al., 2026)

lethal, with Scer\GAL4^how-24B

(Parra-Torres et al., 2026)

lethal, with Scer\GAL4^repo.PL

(Parra-Torres et al., 2026)

lethal, with Scer\GAL4^Toll-6-D42

(Parra-Torres et al., 2026)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is an enhancer of visible | adult stage phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is an enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PY, Zzzz\GGGGCC^49.UAS

(Parra-Torres et al., 2026)

NOT Enhancer of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a non-enhancer of visible | adult stage phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Suppressor of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of visible | adult stage phenotype of Hsap\TARDBP^Q331K.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of abnormal size | adult stage phenotype of Hsap\TARDBP^Q331K.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of visible | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of abnormal size | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^{elav.Switch.PO} is a suppressor | partially of short lived phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^{elav.Switch.PO}

(Parra-Torres et al., 2026)

NOT Suppressor of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a non-suppressor of visible | adult stage phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Phenotype Manifest In

Enhancer of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is an enhancer of eye phenotype of Hsap\ATXN1^82Q.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is an enhancer of eye phenotype of Scer\GAL4^GMR.PY, Zzzz\GGGGCC^49.UAS

(Parra-Torres et al., 2026)

NOT Enhancer of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a non-enhancer of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Suppressor of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of retina | adult stage phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of eye phenotype of Hsap\TARDBP^Q331K.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of retina | adult stage phenotype of Hsap\TARDBP^Q331K.UAS, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a suppressor of eye phenotype of Hsap\TARDBP^UAS.cPTa, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

NOT Suppressor of

Statement

Reference

Nsun1^HMC04440, Scer\GAL4^GMR.PY is a non-suppressor of eye phenotype of Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}, Scer\GAL4^GMR.PY

(Parra-Torres et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

56998

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04440}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG8545^HMC04440

Nsun1^HMC04440

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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