FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-279sponge.UASp.DsRed(Unk)
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General Information
Symbol
Dmel\mir-279sponge.UASp.DsRed(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0299700
Feature type
allele
Associated gene
Dmel\mir-279
Associated Insertion(s)
Carried in Construct
P{UASp-DsRed.mir-279.sponge}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Yoon et al., 2011)
Progenitor genotype
Carried in construct
P{UASp-DsRed.mir-279.sponge}
Cytology
Description

UASp regulatory sequences drive expression of a mir-279 "sponge" sequence, which consists of three copies of the mir-279 binding site inserted into 3'UTR sequence downstream of the DsRed(Unk) coding region.

(Yoon et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
mir-279
Tagged with
DsRed(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of two copies of mir-279sponge.Scer\UAS.P\T.T:Disc\RFP under the control of Scer\GAL4mir-279.PC decreases mir-279 function and results in ectopic invasive cells in approximately 30% of mutant egg chambers. The number of border cells within the main cluster remains normal, indicating the abnormal invasion of follicle cells.

      Expression of two copies of Disc\RFPmir-279-bs.Scer\UAS.P\T under the control of Scer\GAL4mir-279.PC decreases mir-279 function and results in ectopic invasive cells in approximately 30% of mutant egg chambers. The number of border cells within the main cluster remains normal, indicating the abnormal invasion of follicle cells.

      The presence of ectopic cells or clusters of cells in egg chambers expressing Disc\RFPmir-279-bs.Scer\UAS.P\T under the control of Scer\GAL4slbo.2.6 is ameliorated by the presence of mir-279+t3.

      (Yoon et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      The presence of ectopic cells or clusters of cells in egg chambers expressing mir-279sponge.Scer\UAS.P\T.T:Disc\RFP under the control of Scer\GAL4slbo.2.6 is ameliorated by the presence of mir-279+t3.

      (Yoon et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Disc\RFPmir-279-bs.Scer\UAS.P\T
      mir-279sponge.Scer\UAS.P\T.T:Disc\RFP
      mir-279sponge.UASp.DsRed(Unk)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0285335
      References (3)