FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CdsGS8005
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General Information
Symbol
Dmel\CdsGS8005
Species
D. melanogaster
Name
FlyBase ID
FBal0300871
Feature type
allele
Associated gene
Dmel\Cds
Associated Insertion(s)
P{GSV3}CdsGS8005
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Liu et al., 2014)
Progenitor genotype
Associated Insertion(s)
P{GSV3}CdsGS8005
Cytology
Description

P{GSV3}CdsAGS8005 is inserted into the second exon of CdsA and disrupts transcription.

(Liu et al., 2014)
Allele components
Component
Use(s)
Inserted element
P{GSV3}
Regulatory region(s)
UASt
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CdsAGS8005 animals die at late embryonic to early larval stages.

      CdsAGS8005 mutant salivary gland clones are smaller in size and accumulate large amounts of fat compared to neighbouring control cells, demonstrating CdsA acts cell-autonomously. On average, the size of CdsAGS8005 mutant salivary gland cells is only about 20% of wild-type cells.

      In contrast to the small size and massive neutral lipid storage of CdsAGS8005 mutant salivary gland cells, CdsAGS8005 mutant fat body cells are normal in size and fat storage.

      (Liu et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CdsGS8005
      CdsAGS8005
      (Liu et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)