FB2026_02 , released June 18, 2026
Allele: Dmel\eIF3eFrag.UAS.GFP
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General Information
Symbol
Dmel\eIF3eFrag.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0302880
Feature type
allele
Associated gene
Dmel\eIF3e
Associated Insertion(s)
Carried in Construct
P{UAS-eIF3e.Frag.GFP}
Key Links
Transgenic product class
inframe_deletion
(Richardson, 2015.3.11)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Richardson, 2015.3.11)
Mutagen
in vitro construct
(Richardson, 2015.3.11)
Progenitor genotype
Carried in construct
P{UAS-eIF3e.Frag.GFP}
Cytology
Description

Carries amino acids 1-138 of eIF3e tagged at the C-terminus with GFP under the control of UAS. The truncation is based on a potentially oncogenic form of Int6 found in humans.

(Richardson, 2015.3.11)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
eIF3e
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      This allele represents a human variant implicated in disease.
      (Richardson, 2015.3.11)

      Disease model in flies has not been developed.

      EIF3E:p.Cys141_Tyr445del
      (FlyBase curators, 2019-)
      Variants Synonym(s)
      Associated human disease model(s)
        External database links
        Comments concerning this variant

        Closely related variant: EIF3E:p.F154LfsTer13 (COSMIC, COSM5074435).

        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Int6Frag.Scer\UAS.T:Avic\GFP
        eIF3eFrag.Scer\UAS.T:Avic\GFP
        eIF3eFrag.UAS.GFP
        Name Synonyms
        Secondary FlyBase IDs
          References (2)