FB2026_02 , released June 18, 2026
Allele: Dmel\E(spl)mβ-HLH10-1
Open Close
General Information
Symbol
Dmel\E(spl)mβ-HLH10-1
Species
D. melanogaster
Name
FlyBase ID
FBal0302961
Feature type
allele
Associated gene
Dmel\E(spl)mβ-HLH
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Lu and Li, 2015)
Mutagen
Delta2-3 transposase
(Lu and Li, 2015)
Progenitor genotype
P{EP}G8712
(Lu and Li, 2015)
Cytology
Description

Imprecise excision of P{EP}G8712 resulting in a 404 bp deletion from the 5' UTR to the middle of the coding exon of E(spl)mβ-HLH.

(Lu and Li, 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:26,005,622..26,006,025 [-]
Comment:

A 404 bp deletion resulting from the imprecise excision of P{EP}G8712, removes the ATG and more than half of the coding sequence of E(spl)mbeta-HLH. 13 bases of P element sequence remain at the site of the excision. The extent of the deletion was mapped from reported sequence data.

(Lu and Li, 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      E(spl)mβ-HLH10-1 is homozygous viable. No obvious defects in tissue homeostasis are observed in E(spl)mβ-HLH10-1 mutants.

      (Lu and Li, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E(spl)mbeta10-1
      (Lu and Li, 2015)
      E(spl)mβ-HLH10-1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)