FB2026_02 , released June 18, 2026
Allele: Dmel\Cul4UAS.cSa
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General Information
Symbol
Dmel\Cul4UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Szuplewski
FlyBase ID
FBal0304111
Feature type
allele
Associated gene
Dmel\Cul4
Associated Insertion(s)
Carried in Construct
P{UAS-Cul4.S}
Key Links
Transgenic product class
wild_type
(Szuplewski et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Szuplewski et al., 2012)
Mutagen
in vitro construct
(Szuplewski et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Cul4.S}
Cytology
Description

UAS regulatory sequences drive expression of Cul4 in which the endogenous 3'UTR has been replaced by the SV40 3'UTR (this renders the transgene insensitive to regulation by mir-5).

(Szuplewski et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cul4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Cul4Scer\UAS.cSa abrogates the ability of P{UAS-DsRed2-mir-286.mir-4.mir-5} to suppress the reduction in size of the thoracic macrochaetae caused by expression of miGD11624 under the control of Scer\GAL4sca.PU, restoring the mutant phenotype.

      (Szuplewski et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Cul4Scer\UAS.cSa
      Cul4UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Szuplewski
      Secondary FlyBase IDs
        References (1)