FB2026_03 , released September 17, 2026
Allele: Dmel\Uhg11
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General Information
Symbol
Dmel\Uhg11
Species
D. melanogaster
Name
FlyBase ID
FBal0304744
Feature type
allele
Associated gene
Dmel\Uhg1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Herter et al., 2015)
Progenitor genotype
P{EP}Uhg1G11659
(Herter et al., 2015)
Cytology
Description

Imprecise excision of the P{EP}Uhg1G11659 insertion, resulting in a deletion (coordinates 2R:13586606..13590803 , release 5 genome) that removes the transcription unit of the snoRNA host gene Uhg1. This deletion removes the coding regions for all the snoRNAs that are encoded by the introns of the host Uhg1 gene.

(Herter et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:17,699,101..17,703,298 [+]
Comment:

4.2 kb deletion resulting from the imprecise excision of P{EP}Uhg1G11659 reported at 2R:13586606..13590803 in R5 coordinates.

(Herter et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      66% of homozygous females and 50% of homozygous males survive to adulthood. Homozygous females (but not homozygous males) show strongly reduced fertility.

      Homozygotes grow at a significantly slower rate than normal, and adult eclosion is delayed by approximately 12 hours.

      (Herter et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Uhg11/Uhg11 partially suppresses the increase in average nucleus area compared to controls which is seen when MycScer\UAS.cUa is expressed under the control of Scer\GAL4Act.PU in salivary gland clones.

      (Herter et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Uhg11
      (Herter et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)