FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\barkN43
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General Information
Symbol
Dmel\barkN43
Species
D. melanogaster
Name
FlyBase ID
FBal0314310
Feature type
allele
Associated gene
Dmel\bark
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Byri et al., 2015)
Mutagen
ethyl methanesulfonate
(Byri et al., 2015)
Progenitor genotype
Cytology
Description

5' splice site mutation in intron 9 of bark leading to a premature stop codon in region III and truncation of the protein (at 2394 aa) before the CLECT domain in the extracellular part.

(Byri et al., 2015)

Nucleotide substitution: G7491A.

(Byri et al., 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:3,799,854..3,799,854 [+]
Nucleotide change:

G3799854A

Reported nucleotide change:

G7491A

Comment:

G to A mutation in the 5' splice junction of intron 9 leads to early translation termination.

(Byri et al., 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show excessively elongated tracheal tubes.

      (Byri et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      akaN43
      (Byri et al., 2015)
      barkN43
      Name Synonyms
      Secondary FlyBase IDs
        References (1)