FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\drongoHMJ22758
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General Information
Symbol
Dmel\drongoHMJ22758
Species
D. melanogaster
Name
FlyBase ID
FBal0315255
Feature type
allele
Associated gene
Dmel\drongo
Associated Insertion(s)
Carried in Construct
P{TRiP.HMJ22758}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HMJ22758}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMJ22758
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of drongoHMJ22758 under the combined control of the Scer\GAL4otu.T:Hsim\VP16, Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16 drivers leads to pleiotropic egg chamber defects: Some eggs contain a double dose of cells (total of 32, 30 nurse cells, 2 oocytes) due to faulty splitting or adhesion of follicle cells and their two oocytes are positioned randomly. In other cases the egg chamber is completely malformed consisting of abnormally wide band of follicle cells surrounding a few cells resembling nurse cells. Other defects seem to be due to an extra round of cystoblast division as the egg chambers contain 32 cells but with just one oocyte. However, most egg chambers appear to develop normally and can be fertilized and deposited normally and also hatch at rates comparable to wild-type.

      (Catrina et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      drongoHMJ22758
      drongoiHMJ
      (Catrina et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)