FB2026_02 , released June 18, 2026
Allele: Dmel\Neurl4Δ2
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General Information
Symbol
Dmel\Neurl4Δ2
Species
D. melanogaster
Name
FlyBase ID
FBal0316517
Feature type
allele
Associated gene
Dmel\Neurl4
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Jones and Macdonald, 2015)
Progenitor genotype
P{EPgy2}Neurl4EY12221
(Jones and Macdonald, 2015)
Cytology
Description

Imprecise excision of P{EPgy2}Neurl4EY12221. The first exon and a portion of the second exon are deleted, as well as 409 bp upstream of the transcription start site of Neurl4.

(Jones and Macdonald, 2015)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:14,049,277..14,050,301 [-]
Comment:

Approximate boundaries of a deletion resulting from the imprecise excision of P{EPgy2}Neurl4EY12221. The deletion was reported to remove exon 1 and a portion of exon 2 of Neurl4 as well as 409 bp upstream of the Neurl4 transcription start site.

(Jones and Macdonald, 2015)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Neurl4Δ1 mutants display a dominant misshapen primordial germ cells (PGC) in well over half of the embryos from heterozygous mothers.

      (Jones and Macdonald, 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Neurl4Δ2
      (Jones and Macdonald, 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)