FB2026_03 , released September 17, 2026
Allele: Dmel\halot3.2
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General Information
Symbol
Dmel\halot3.2
Species
D. melanogaster
Name
FlyBase ID
FBal0319119
Feature type
allele
Associated gene
Dmel\halo
Associated Insertion(s)
Carried in Construct
P{halo.3.2}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Arora et al., 2016)
wild_type
(Arora et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Arora et al., 2016)
wild_type
(Arora et al., 2016)
Mutagen
in vitro construct
(Arora et al., 2016)
Progenitor genotype
Carried in construct
P{halo.3.2}
Cytology
Description

3.2kb genomic region encompassing halo (coordinates 2L:1517488..1520710 release 6 genome).

(Arora et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
halo
Encoded product / tool
halo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2L:1,517,488..1,520,710 [-]
Comment:

halo rescue fragment

(Arora et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Increased halo dosage (halot3.2/halot3.2) in embryos results in an earlier inward shift and overall greater inward displacement of lipid droplets (comparing embryos with 0 - 4 copies of halo using combinations of halo3.2.T:Ivir\HA1 and Df(2L)ΔhaloAJ).

      (Arora et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      KhcUbi-p63E.T:Hsap\MYC overexpression attenuates net motion of lipid droplets in the plus-end direction, with the droplet population shifting inwards as halo dosage increases (phase II embryos).

      (Arora et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      halot3.2 partially rescues Df(2L)ΔhaloAJ

      (Arora et al., 2016)
      Comments

      Two copies of halot3.2 restores net inward lipid droplet transport substantially but not completely in Df(2L)ΔhaloAJ/Df(2L)ΔhaloAJ embryos (phase IIa, cycle 13 to mid-cellularization).

      (Arora et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      halot3.2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)