FB2026_03 , released September 17, 2026
Allele: Dmel\glob1UAS.cGa
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General Information
Symbol
Dmel\glob1UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Gleixner
FlyBase ID
FBal0319256
Feature type
allele
Associated gene
Dmel\glob1
Associated Insertion(s)
Carried in Construct
P{UAS-glob1.G}
Key Links
Transgenic product class
cDNA
(Gleixner et al., 2016)
wild_type
(Gleixner et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Gleixner et al., 2016)
wild_type
(Gleixner et al., 2016)
Mutagen
in vitro construct
(Gleixner et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-glob1.G}
Cytology
Description

UASt regulatory sequences drive expression of a glob1 cDNA.

(Gleixner et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
glob1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of glob1Scer\UAS.cGa under the control of Scer\GAL4da.G32 in either long term hypoxic conditions or short term severe hypoxic conditions does not change survival rate relative to controls, nor does it affect reaction time to anoxia, and recovery time post-anoxia.

      Expression of glob1Scer\UAS.cGa under the control of Scer\GAL4da.G32 in normoxic conditions results in no significant change in lifespan or length of developmental stages, and does not change survival rate when exposed to paraquat-induced oxidative stress or hyperoxia.

      No difference in the amount of lipid peroxidation or oxidative DNA damage observed in adult flies expressing glob1Scer\UAS.cGa under the control of Scer\GAL4da.G32 when exposed to oxidative stress via paraquat or hyperoxia.

      (Gleixner et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      glob1Scer\UAS.cGa
      glob1UAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Gleixner
      Secondary FlyBase IDs
        References (1)