FB2026_02 , released June 18, 2026
Allele: Dmel\CycGCreD
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General Information
Symbol
Dmel\CycGCreD
Species
D. melanogaster
Name
FlyBase ID
FBal0319285
Feature type
allele
Associated gene
Dmel\CycG
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Nagel et al., 2016)
Mutagen
I-CreI
(Nagel et al., 2016)
Progenitor genotype
Cytology
Description

Contains a single mutant copy of CycG. Derived by removing the proximal copy of CycG and the w+mW.hs marker from Dp(3;3)CycGHR7.

(Nagel et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Stage 10 ovaries of the CycGCreD homozygous mutants display aberrant relative positioning of border and centripetal cells and the shape of the border between the oocyte and nurse cells is perturbed compared to controls.

      At stage 13-14 some CycGCreD/CycGCreD ovaries show dumpless phenotype (remains of apoptosed nurse cells are present beyond stage 14), though the penetrance is low.

      (Nagel et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      CycGCreD, Df(1)N-54l9/+ has visible phenotype

      (Nagel et al., 2016)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      CycGCreD has wing vein | adult stage phenotype, suppressible by Df(1)N-54l9/+

      (Nagel et al., 2016)
      Other
      Statement
      Reference

      CycGCreD, Df(1)N-54l9/+ has wing blade phenotype

      (Nagel et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the wing notching in CycGCreD/+;Df(1)N-54l9/+ double heterozygote adult flies is about the same as in Df(1)N-54l9/+ single heterozygotes but is decreased in CycGCreD/CycGCreD;Df(1)N-54l9/+ flies.

      (Nagel et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CycGCreD
      cycGCreD
      (Nagel et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)