FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Usp47C-S.UAS.Tag:FLAG
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General Information
Symbol
Dmel\Usp47C-S.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0319679
Feature type
allele
Associated gene
Dmel\Usp47
Associated Insertion(s)
Carried in Construct
PBac{UAS-Usp47.C-S}
Key Links
Transgenic product class
dominant_negative_variant
(Shi et al., 2015)
missense_variant
(Shi et al., 2015)
Mutagen
    Nature of the Allele
    Transgenic product class
    dominant_negative_variant
    (Shi et al., 2015)
    missense_variant
    (Shi et al., 2015)
    Mutagen
    Progenitor genotype
    Carried in construct
    PBac{UAS-Usp47.C-S}
    Cytology
    Description

    UAS regulatory sequences drive expression of dominant negative form of Usp47 (the catalytic Cys residue in the catalytic domain is mutated) that is tagged Tag:FLAG.

    (Shi et al., 2015)
    Allele components
    Component
    Use(s)
    Regulatory region(s)
    UAS
    Encoded product / tool
    Usp47
    Tagged with
    Tag:FLAG
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of Usp47C-S.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Bx-MS1096 results in severe adult wing malformation.

        (Shi et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Usp47C-S.Scer\UAS.T:Zzzz\FLAG
        Usp47C-S.UAS.Tag:FLAG
        Name Synonyms
        Secondary FlyBase IDs
          References (1)