FB2026_02 , released June 18, 2026
Allele: Dmel\Dis33
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General Information
Symbol
Dmel\Dis33
Species
D. melanogaster
Name
FlyBase ID
FBal0319958
Feature type
allele
Associated gene
Dmel\Dis3
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Snee et al., 2016)
Mutagen
ethyl methanesulfonate
(Snee et al., 2016)
Progenitor genotype
Cytology
Description

Amino acid replacement: C483term.

(Snee et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:24,335,056..24,335,056 [+]
Nucleotide change:

C24335056A

Amino acid change:

C483term | Dis3-PA; C483term | Dis3-PB

Reported amino acid change:

C483term

Comment:

Dis33 is reported as a nonsense mutation at amino acid position 483 (The inferred nucleotide change is TGC to TGA). The reported nucleotide change of C1624T would not lead to a change in the amino acid residue at this position.

(Snee et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dis33/Dis33 mutants survive at the second instar larval stage for an extended period and then die.

      (Snee et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dis33
      dis33
      (Snee et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)