FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bsd3a52a
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General Information
Symbol
Dmel\bsd3a52a
Species
D. melanogaster
Name
FlyBase ID
FBal0321100
Feature type
allele
Associated gene
Dmel\bsd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(McCracken and Locke, 2014)
Mutagen
ethyl methanesulfonate
(McCracken and Locke, 2014)
Progenitor genotype
Cytology
Description

A G/C to A/T transition resulting in a premature stop codon at the amino terminal end of the first predicted STKc domain and therefore likely to be a null allele.

(McCracken and Locke, 2014)

Amino acid replacement: W123term.

(McCracken and Locke, 2014)

Nucleotide substitution: G675A.

(McCracken and Locke, 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:12,149,609..12,149,609 [-]
Nucleotide change:

G12149609A

Reported nucleotide change:

G675A

Amino acid change:

W123term | bsd-PA; W123term | bsd-PB; W123term | bsd-PC

Reported amino acid change:

W123term

Comment:

TGG to TGA (Opal) nonsense mutation.

(McCracken and Locke, 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CG88783a52a/+ significantly enhances white-eyed variegation in gypsy{}ciE1/+ flies, significantly enhances white-eyed variegation in P{lacW}ciDplac/+ flies, and significantly enhances white-eyed variegation in In(1)wm4/+ flies.

      (McCracken and Locke, 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      3a52a
      (McCracken and Locke, 2014)
      CG88783a52a
      bsd3a52a
      Name Synonyms
      Secondary FlyBase IDs
        References (1)