FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Crub\Vn50UASp.cTa
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General Information
Symbol
Crub\Vn50UASp.cTa
Species
C. rubecula
Name
FlyBase ID
FBal0321253
Feature type
allele
Associated gene
Crub\Vn50
Associated Insertion(s)
Carried in Construct
P{UASp-Vn50.T}
Transgenic product class
wild_type
(Thomas et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Thomas et al., 2010)
Mutagen
in vitro construct
(Thomas et al., 2010)
Progenitor genotype
Carried in construct
P{UASp-Vn50.T}
Cytology
Description

UASp regulatory sequences drive expression of Crub\Vn50.

(Thomas et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Crub\Vn50
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Compared with wild-type, the difference in melanization of flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 is statistically significant in females whereas it is not in males.

      Compared to wild-type, there is no significant change in survival of the flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 when challenged with the pathogenic bacterium Serratia marcescens.

      The survivability against Beauveria bassiana of male flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 is not significantly different from that of controls. However, female flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 suffer reduced survival when treated with the Beauveria fungus compared with control females.

      Both male and female flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 show a delay in Drosophila C virus (DCV)-induced mortality.

      Flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 show accelerated development eclose one day earlier than controls.

      The total number of progeny produced from three days of egg laying is significantly greater for flies expressing Zzzz\Vn50Scer\UAS.P\T.cTa under the control of Scer\GAL4da.G32 than the control flies.

      (Thomas et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Crub\Vn50Scer\UAS.P\T.cTa
      Crub\Vn50UASp.cTa
      Zzzz\Vn50Scer\UAS.P\T.cTa
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0320639
      • FBal0282592
      References (2)