UAS regulatory sequences drive expression of Hsap\DISC1 amino acid residues 1-402. The protein is tagged with Tag:HA.
The axonal as well as dendritic branching of γ-neurons in MARCM somatic clones in the adult mushroom body expressing Hsap\DISC11-402.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ey-OK107 is not significantly affected compared to wild-type.
Expression of Hsap\DISC11-402.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4tub.PU has no significant effect on the neuromuscular junction structure and morphology i third instar larvae: the total bouton area, number of boutons as well axonal branching points are all normal.