FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SA186
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General Information
Symbol
Dmel\SA186
Species
D. melanogaster
Name
FlyBase ID
FBal0321762
Feature type
allele
Associated gene
Dmel\SA1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gyuricza et al., 2016)
Progenitor genotype
P{EPgy2}EY20282
(Gyuricza et al., 2016)
Cytology
Description

Imprecise excision of the P{EPgy2}EY20282 insertion, resulting in a deletion of more than 96bp but less than 813bp of the SA coding region.

(Gyuricza et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Oocytes in SA86 mutant germline clone display defects in synaptonemal complex assembly and the average number of c(3)G-positive patches significantly decreases between regions 2a and 3 compared to control germaria. The number of Cenp-C-labelled foci per cell at metaphase I in stage 14 oocytes is however not changed compared to wild-type, suggesting that sister-centromere adhesion is unaffected.

      (Gyuricza et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SA186
      SA86
      (Gyuricza et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)