FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\peac89
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General Information
Symbol
Dmel\peac89
Species
D. melanogaster
Name
FlyBase ID
FBal0323144
Feature type
allele
Associated gene
Dmel\pea
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Klusza et al., 2013)
Progenitor genotype
P{A92}pea1
(Klusza et al., 2013)
Cytology
Description

746bp deletion that removes part of the 5'UTR, the transcription start site and some of the coding sequence of pea. Generated by imprecise excision of P{A92}pea1.

(Klusza et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:14,153,139..14,153,884 [+]
Comment:

Approximate coordinates of 746 bp deletion resulting from the imprecise excision of P{A92}pea1. Extends from the insertion site in the 5' UTR of pea into the pea gene.

(Klusza et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      peac89/peac89, but not peac89/+, mutants exhibit lethality.

      peac89/peac89 whole germline clones in peac89/+ females arrest during stages 2-3 of oogenesis, however, egg chambers mosaic for peac89/peac89 germline clones develop further in oogenesis, exhibiting nurse cell chromatin dispersal defects at a high penetrance, mis-localization of spliceosomes, various nurse cell chromatin defects at later stages, including granular and/or prominent interchromatin spaces, irregularities in the shape and morphology of heterozygous sibling nurse cells, and occasional growth defects from stage 6-10 of oogenesis, as compared to wild type.

      (Klusza et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Not rescued by

      peac89 is not rescued by peaUASp.EGFP/Scer\GAL4VP16.mat.αTub67C

      (Klusza et al., 2013)
      Comments

      Expression of peaScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 fails to rescue the egg chamber and nurse cell defects seen in peac89/peac89 germline clones.

      (Klusza et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      peaC89
      (Klusza et al., 2013)
      peac89
      (Klusza et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)